发明名称 |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy |
摘要 |
The subject invention concerns a recombinant adeno-associated virus vector characterized as being capable of delivering and expressing at least one mammalian gene into a genome of a mammalian host cell such that the expression of the gene is regulated in a tissue specific manner by cis-acting regulatory and promoter elements of the gene. A method of using this recombinant adeno-associated virus vector for therapeutic purposes is also provided.
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申请公布号 |
US6268213(B1) |
申请公布日期 |
2001.07.31 |
申请号 |
US19950475470 |
申请日期 |
1995.06.07 |
申请人 |
SAMULSKI RICHARD JUDE;WALSH CHRISTOPHER E.;NIENHUIS ARTHUR W.;LIU JOHNSON M.;MILLER JEFFREY L. |
发明人 |
SAMULSKI RICHARD JUDE;WALSH CHRISTOPHER E.;NIENHUIS ARTHUR W.;LIU JOHNSON M.;MILLER JEFFREY L. |
分类号 |
A61K48/00;C12N7/01;C12N15/861;(IPC1-7):C12N15/86 |
主分类号 |
A61K48/00 |
代理机构 |
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地址 |
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