| 发明名称 |
Sperm specific lysozyme-like proteins |
| 摘要 |
The present invention relates to two novel, testis-specific proteins (C19 and C23) that are lysozyme paralogues. The proteins are believed to play a role in capacitation of sperm and the fertilization of the ovum. Therefore these compounds make ideal targets for the design of contraceptive agents. The C19 and C23 proteins can also be modified to establish lysozyme activity and the modified proteins can then be used in all applications that currently exist for lysozymes. |
| 申请公布号 |
AU3097301(A) |
申请公布日期 |
2001.07.31 |
| 申请号 |
AU20010030973 |
申请日期 |
2001.01.19 |
| 申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
JOHN C. HERR;FRIEDERIKE JAYES;ARABINDA MANDAL;JAGATHPALA SHETTY;MICHAEL J. WOLKOWICZ |
| 分类号 |
C12N15/09;A61K38/46;A61K39/00;A61K39/395;A61P15/18;A61P31/04;A61P31/12;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/36;C12N15/12;C12N15/56;C12Q1/02 |
主分类号 |
C12N15/09 |
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