发明名称 |
Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative |
摘要 |
This invention is to provide a pharmaceutical composition for antagonizing CCR5 which comprises a compound of the formula:wherein R1 is an optionally substituted 5- to 6-membered ring; W is a divalent group of the formula:wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof.
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申请公布号 |
US6268354(B1) |
申请公布日期 |
2001.07.31 |
申请号 |
US20000661320 |
申请日期 |
2000.09.13 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
NISHIMURA OSAMU;BABA MASANORI;SAWADA HIDEKAZU;KANZAKI NAOYUKI;KUROSHIMA KEN-ICHI;SHIRAISHI MITSURU;ARAMAKI YOSHIO |
分类号 |
A61K31/335;A61K31/351;A61K31/452;A61K31/4523;A61K31/5377;A61K31/665;A61K31/67;A61K45/06;C07C233/62;C07D309/14;C07D313/08;C07D337/08;C07D407/12;(IPC1-7):A61K31/165;A61K31/445;C07C233/11;C07D211/06 |
主分类号 |
A61K31/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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