| 发明名称 |
Src family SH2 domain inhibitors |
| 摘要 |
This invention relates to compounds of formula (1):wherein Ring a, A, B, C, D, E, R and Q are defined herein. These compounds possess the ability to disrupt the interaction between regulatory proteins possessing one or more SH2 domains and their native ligands.
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| 申请公布号 |
US6268365(B1) |
申请公布日期 |
2001.07.31 |
| 申请号 |
US19990438629 |
申请日期 |
1999.11.12 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
BETAGERI RAJASHEKHAR;BEAULIEU PIERRE L.;FERLAND JEAN-MARIE;LLINAS-BRUNET MONTSE;MOSS NEIL;PATEL USHA;PROUDFOOT JOHN R.;CARDOZO MARIO |
| 分类号 |
C07D237/22;A61K31/44;A61K31/4409;A61K31/4418;A61K31/4425;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4725;A61K31/50;A61P1/04;A61P3/10;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D213/75;C07D401/12;C07D405/04;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D417/14;(IPC1-7):A61K31/501;C07D237/02 |
主分类号 |
C07D237/22 |
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