| 发明名称 |
Identification of drug candidates modulating factor VII-mediated intracellular signaling |
| 摘要 |
The present invention provides methods for identifying candidate drugs that modulate factor VIIa-mediated intracellular signaling by measuring the effects of such drugs on the activation of the mitogen-activated protein kinase (MAP kinase) signaling pathway.
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| 申请公布号 |
US6268163(B1) |
申请公布日期 |
2001.07.31 |
| 申请号 |
US19980116748 |
申请日期 |
1998.07.16 |
| 申请人 |
NOVO NORDISK A/S |
发明人 |
KONGSBAK LARS;BERGENHEM NIELS;PETERSEN LARS CHRISTIAN;THASTRUP OLE;FOSTER DON |
| 分类号 |
G01N33/50;A61K31/415;A61K31/4192;A61K31/4375;A61K31/4427;A61K31/4439;A61K31/498;A61K38/46;A61K38/48;A61K45/00;A61P9/00;A61P9/10;A61P35/00;A61P43/00;C07D231/12;C07D241/44;C07D249/04;C07D401/04;C07D471/04;C12Q1/06;G01N33/15;G01N33/86;(IPC1-7):C12Q1/48;G01N33/53 |
主分类号 |
G01N33/50 |
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