Transdermal device for the delivery of testosterone

摘要

A device for the transdermal delivery of testosterone comprising a backing having an adhesive layer adhered to one surface of the backing, said adhesive layer comprising: (a) a pressure sensitive skin adhesive that comprises a copolymer of (i) isooctyl acrylate and (ii) one or more ethylenically unsaturated B monomers containing a functional group selected from the group consisting of carboxylic acid, sulfonamide, urea, carbamate, carboxamide, hydroxy, amino, oxy, oxo and cyano; (b) a therapeutically effective amount of testosterone; and (c) a delivery enhancing adjuvant comprising a terpene.