发明名称 PROCESS FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE AND ITS USE FOR THE PRODUCTION OF CITALOPRAM
摘要 <p>There is described a process for the preparation of 5-carboxyphthalide, which comprises adding terephthalic acid to fuming sulfuric acid containing at least 20% by weight of SO3, then adding formaldehyde to the mixture, heating the mixture at a temperature of 120-145 °C and isolating 5-carboxyphthalide from the reaction mixture.</p>
申请公布号 WO2001053284(A1) 申请公布日期 2001.07.26
申请号 EP2001000617 申请日期 2001.01.17
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