METHOD FOR DETECTION OR DETERMINATION IF ENVIRONMENTAL HORMONES

摘要

A method of detecting or quantifying environmental hormones (in particular, dioxins) in a sample with the use of granulosa cells, etc. In this method, changes in the expression dose of a luteinizing hormone receptor induced by follicle-stimulating hormone, etc. in the granulosa cells are employed as an indication for detecting or quantifying dioxins. A contraceptive method characterized by inhibiting the expression of luteinizing hormone receptor induced by follicle-stimulating hormone in granulosa cells; and contraceptiv e agents containing a substance inhibiting the expression of luteinizing hormo ne receptor as the active ingredient.