发明名称 Physiologically active substance eem-s originating in mushrooms, process for producing the same and drugs
摘要 EEM-S having a molecular weight of 6000-60000 and obtained by: (i) extracting organisms such as Lentinus edodes, Flammulina velutipes, Hypsizigus marmoreus, Ganoderma lucidumand/or Phellinus yucatensiswith hot water or lower alcohol; and (ii) treating the extract with molecular sieves to remove the low molecular weight and high molecular weight fractions. EEM-S is claimed having a molecular weight of 6000-60000 and obtained by: (i) extracting Lentinus edodes, Flammulina velutipes, Hypsizigus marmoreus, Pleurotus ostreatus, Pholiota nameko, Grifola fondosa, Volvariella speciosa var.speciosa, Lyophyllum decastes, blanc du pays, Tricholoma matsutake, Ganoderma lucidumand/or Phellinus yucatensiswith hot water or lower alcohol; and (ii) treating the extract with molecular sieves to remove the low molecular weight and high molecular weight fractions. ACTIVITY : Cytostatic; immunostimulator; hypotensive; antidiabetic. EEM-SB administered to mice implanted with BDF 1cells at 500 mg/kg/day for 20 days increased survival time by 45.8%. MECHANISM OF ACTION : Antioxidant; hypoglycemic.
申请公布号 AU2547901(A) 申请公布日期 2001.07.24
申请号 AU20010025479 申请日期 2001.01.11
申请人 LIFE SCIENCE LABORATORIES CO., LTD. 发明人 TETSURO IKEKAWA;AKIKO IKEKAWA;FUMITAKE SHIMADA
分类号 A61K9/00;A61K9/08;A61K9/14;A61K9/16;A61K9/20;A61K9/28;A61K9/30;A61K9/48;A61K9/62;A61P35/00;A61P37/04 主分类号 A61K9/00
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