摘要 |
A method of making an oral pharmaceutical dosage form of an aqueous soluble drug including the steps of: forming a solution or suspension of the drug, a soluble polymer and a binding or gelling agent; contacting the solution or suspension with an acid precipitating medium allowing the polymer to precipitate to form particles containing the dissolved drug; drying the particles; wherein the gelling or binding agent influences or prevents migration of the drug towards the surface of the particles during drying. |