发明名称 |
Oligomers of nonpeptide restricted mimetics of dipeptides or tripeptides and theuse thereof in the synthesis of synthetic proteins and polypeptides |
摘要 |
The invention relates to nonpeptide oligomers of amino acids. The oligomers comprise -(NR'-A-CO)-O- units which represent a nonpeptide, restricted-mimetic inducer of the beta turn in a dipeptide or tripeptide fragment. Said oligomers may be produced by peptide synthesis techniques, whether in solution or in the solid phase, and can be used in the synthesis of synthetic proteins or polypeptides, in which the peptide fragment(s) (is) are identical to those of the corresponding natural protein or polypeptide and whose structural fragment(s) comprise(s) a fragment of an oligomer according to the invention. |
申请公布号 |
AU3188101(A) |
申请公布日期 |
2001.07.24 |
申请号 |
AU20010031881 |
申请日期 |
2001.01.11 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
MURIEL AMBLARD;JEAN MARTINEZ;GILBERT BERGE |
分类号 |
C07D281/10;C07D207/26;C07K1/02;C07K5/078;C07K5/097;C07K7/02;C07K14/575;C07K14/695;C08G69/10 |
主分类号 |
C07D281/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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