| 摘要 |
PROBLEM TO BE SOLVED: To provide a collunarium exhibiting excellent prophylactic and therapeutic effect upon allergic rhinitis or the like. SOLUTION: This collunarium comprises a compound represented by formula (I) [wherein Ar1 and Ar2 are an aromatic group and may be combined with adjacent carbon into a condensed ring group; B ring is a nitrogen-containing heterocycle; X and Y are each a direct bond, O, S(O)p (wherein p is 0 to 2), NR4 (wherein R4 is H or a lower alkyl) or a bivalent normal lower hydrocarbon group allowed to have one to three intervening hetero atoms; A is N or CR7 (wherein R7 is H, a halogen atom, a hydrocarbon group, an acyl group or hydroxyl group allowed to have a substituent; R1, R2 and R3 are each H, a halogen atom, a hydrocarbon group, an acyl group or hydroxyl group allowed to have a substituent; R8 is) II], or its salt or prodrug.
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