Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung

摘要

The invention relates to fused pyrrole compounds of formula (I), wherein at least one of the radicals R1, R2, R3 represent 4-sulfur-substituted phenyl. The invention specifically concerns pyrrolizines, indolizines and heteroanalogues with a selective inhibitory effect on isoenzyme-2 of the prostaglandin-H-synthase (COX-2). The invention also relates to pharmaceutical agents that contain these compounds, and to the use of these compounds for treating diseases of the rheumatic form-cycle.