发明名称 |
O-METHYLATED RAPAMYCIN DERIVATIVES FOR ALLEVIATION AND INHIBITION OF LYMPHOPROLIFERATIVE DISORDERS |
摘要 |
The present invention relates to methods of alleviating and inhibiting a lymphoproliferative disorder in a mammal, the method comprising administering one or more rapamycin derivatives (including rapamycin) to the mammal (see figure 8). Further, the invention provides a method for identifying agents which are useful for alleviating and inhibiting lymphoproliferative disorders, as well as a method for identifying agents which are capable of inhibiting metastasis of lymphatic tumors in a mammal.
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申请公布号 |
WO0151049(A1) |
申请公布日期 |
2001.07.19 |
申请号 |
WO2001US01537 |
申请日期 |
2001.01.12 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;WASIK, MARIUSZ, A.;SHAW, LESLIE, M. |
发明人 |
WASIK, MARIUSZ, A.;SHAW, LESLIE, M. |
分类号 |
C07D498/18;A61K31/343;A61K31/42;A61K31/436;A61K31/44;A61K31/445;A61K31/4745;A61K31/52;A61K31/664;A61K33/24;A61K38/00;A61K39/395;A61K45/00;A61P35/00;A61P35/02;A61P37/06;G01N33/50;(IPC1-7):A61K31/44 |
主分类号 |
C07D498/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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