Blood processing systems and methods using apparent hematocrit as a process control parameter

摘要

Blood processing systems and methods separate whole blood into red blood cells and a plasma constituent within a rotating centrifugal separation device. The systems and methods convey whole blood into the separation device through an inlet path including a pump operable at a prescribed rate. The systems and methods remove plasma constituent from the separation device through an outlet path including a pump operable at a prescribed rate. The systems and methods derive a value Hb representing an apparent hematocrit of whole blood entering the separation device, where: 1 $H_b=\frac{H_{\mathrm{rbc}}\left(Q_b-Q_p\right)}{Q_b}$ and where Hrbc is a value relating to hematocrit of red blood cells in the separation device. The systems and methods generate outputs and control commands based, at least in part, upon Hb.