发明名称 N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
摘要 Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 US6262302(B1) 申请公布日期 2001.07.17
申请号 US19990398211 申请日期 1999.09.17
申请人 ELAN PHARMACEUTICALS, INC.;ELI LILLY & COMPANY 发明人 WU JING;TUNG JAY S.;NISSEN JEFFREY S.;MABRY THOMAS E.;LATIMER LEE H.;EID CLARK N.;AUDIA JAMES E.
分类号 A61K31/198;A61K31/223;A61K31/277;A61K31/44;(IPC1-7):C07C229/38;C07C233/64;C07D307/00;C07D211/00;C07D213/00 主分类号 A61K31/198
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