发明名称 |
N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds |
摘要 |
Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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申请公布号 |
US6262302(B1) |
申请公布日期 |
2001.07.17 |
申请号 |
US19990398211 |
申请日期 |
1999.09.17 |
申请人 |
ELAN PHARMACEUTICALS, INC.;ELI LILLY & COMPANY |
发明人 |
WU JING;TUNG JAY S.;NISSEN JEFFREY S.;MABRY THOMAS E.;LATIMER LEE H.;EID CLARK N.;AUDIA JAMES E. |
分类号 |
A61K31/198;A61K31/223;A61K31/277;A61K31/44;(IPC1-7):C07C229/38;C07C233/64;C07D307/00;C07D211/00;C07D213/00 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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