发明名称 |
Adamantanecarboximidamide derivatives and their use as NMDA antagonists |
摘要 |
The compound of the above formula wherein R1-R5 are independently selected from hydrogen, alkyl and aryl and prodrugs thereof; and pharmaceutically acceptable salts thereof; and use of the compounds in therapy, particularly for treatment of a condition generally associated with abnormalities in glutamtergic transmission.
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申请公布号 |
US6262106(B1) |
申请公布日期 |
2001.07.17 |
申请号 |
US20000600168 |
申请日期 |
2000.09.13 |
申请人 |
VERNALIS RESEARCH LIMITED |
发明人 |
MONCK NATHANIEL JULIUS THOMAS;GILLESPIE ROGER JOHN;BIRD ANDREW JAMES |
分类号 |
A61K31/155;A61K31/381;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P43/00;C07C257/16;C07D333/24;(IPC1-7):A61K31/38 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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