发明名称 Octahydrobenzo[f]quinoline-based receptor agonists and antagonists
摘要 The present invention relates to a composition, and method of use, of an actahydrobenzo[f]quinoline-based compound represented by the following structural formula:In this formula, R1 is -OH or -OCH3 and R2 is -H, -OH or -OCH3. In addition, R3 is a C1 to C2 saturated or unsaturated, alkyl group. Furthermore, R4 is an aryl group, wherein examples of suitable aryl groups, as defined herein, include phenyl and thienyl groups. The method of this invention relates to the use of the claimed composition to treat psychotic disorders, to treat Parkinson's disease, or to sedate a mammal by administering an effective amount of a claimed composition.
申请公布号 US6262064(B1) 申请公布日期 2001.07.17
申请号 US19990237390 申请日期 1999.01.26
申请人 THE BOARD OF GOVERNORS FOR HIGHER EDUCATION;THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS. 发明人 FROIMOWITZ MARK;JACOB JAMES N.
分类号 A61P25/18;A61P25/20;C07D221/10;C07D409/06;(IPC1-7):A61K31/473;C07D221/06 主分类号 A61P25/18
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