| 发明名称 |
Camptothecin beta-alanine esters with topoisomerase i inibhition |
| 摘要 |
beta-Alanine esters of camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex. |
| 申请公布号 |
AU5453800(A) |
申请公布日期 |
2001.07.16 |
| 申请号 |
AU20000054538 |
申请日期 |
2000.06.14 |
| 申请人 |
MONROE E. WALL;MANSUKH C. WANI;GOVINDARAJAN MANIKUMAR;NEELAKANTAN BALASUBRAMANIAN;DOLATRAI VYAS |
发明人 |
MONROE E. WALL;MANSUKH C. WANI;GOVINDARAJAN MANIKUMAR;NEELAKANTAN BALASUBRAMANIAN;DOLATRAI VYAS |
| 分类号 |
C12N9/99;A61K38/00;A61P35/00;A61P35/02;C07D491/22;C07K5/023 |
主分类号 |
C12N9/99 |
| 代理机构 |
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代理人 |
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