发明名称 CANCER CELL-SPECIFIC GENE EXPRESSION SYSTEM
摘要 The present invention relates to a cancer-specific gene expression system, more particularly to a cancer-specific gene expression system characterized comprising a promoter with a binding site (E2Fbs) for E2F transcription factor expressed only in a cancerous cell and a structural gene. Said gene expression system thus can provide an effective way in conjunction with various combined structural genes to treat cancer by using the special feature of said system that specifically works on cancerous cells without affecting any normal cells.
申请公布号 WO0149868(A1) 申请公布日期 2001.07.12
申请号 WO2000KR00330 申请日期 2000.04.10
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;CHONG KUN DANG PHARMACEUTICAL CORPORATION;YEOM, YOUNG, IL;LIM, MI, JUNG;HAN, JUNG, HEE;LIM, JONG, SEOK;KIM, KWANG, DONG;KIM, CHANG, KYU 发明人 YEOM, YOUNG, IL;LIM, MI, JUNG;HAN, JUNG, HEE;LIM, JONG, SEOK;KIM, KWANG, DONG;KIM, CHANG, KYU
分类号 A61K48/00;C07K14/47;C12N15/63;C12N15/85 主分类号 A61K48/00
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