发明名称 |
NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE |
摘要 |
A heteroaryl derivative having the formula (I) any of its enantiomers or any mixture thereof, or an acid addition salt thereof , wherein X is -O-, -S-, or -CR<4>R<5>-; and Y is -CR<6>R<7>-, -CR<6>R<7>-CR<8>R<9>-, or -CR<6>=CR<7>-; or X and Y together form a group -CR<4>=CR<5>-, or -CR<4>=CR<5>-CR<6>R<7>-; Z is -O-, or -S-; W is N, C, or CH; n is 2, 3, 4, 5, 6, 7, 8, 9 or 10; m is 2 or 3: A is O or S wherein the dotted lines mean an optional bond. The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.
|
申请公布号 |
WO0149683(A1) |
申请公布日期 |
2001.07.12 |
申请号 |
WO2000DK00741 |
申请日期 |
2000.12.29 |
申请人 |
H. LUNDBECK A/S;RUHLAND, THOMAS;KROG-JENSEN, CHRISTIAN;MIKKELSEN, IVAN;ROTTLAENDER, MARIO;MIKKELSEN, GITTE;MOLTZEN, EJNER, KNUD;ANDERSEN, KIM |
发明人 |
RUHLAND, THOMAS;KROG-JENSEN, CHRISTIAN;MIKKELSEN, IVAN;ROTTLAENDER, MARIO;MIKKELSEN, GITTE;MOLTZEN, EJNER, KNUD;ANDERSEN, KIM |
分类号 |
A61K31/496;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D307/78;C07D307/79;C07D319/18;C07D333/54;(IPC1-7):C07D405/04;C07D409/04;A61K31/381 |
主分类号 |
A61K31/496 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|