发明名称 |
Process for preparing protected 4-aminomethyl-pyrrolidin-3-one |
摘要 |
<p>A process for preparing a compound of formula (1) in which P1 and P2 are protecting groups; comprising a) reaction of a compound of formula (5) wherein P1 is as defined for formula (1); with a Raney-nickel catalyst in a solvent under hydrogen to produce a compound of formula (6) wherein P1 is as defined for formula (1); b) protecting the amino group to produce a compound of formula (7) wherein P1 and P2 are as defined for formula (1); and c) selective reduction of the double bond to produce the compound of formula (1).</p> |
申请公布号 |
CZ20003109(A3) |
申请公布日期 |
2001.07.11 |
申请号 |
CZ20000003109 |
申请日期 |
1999.03.04 |
申请人 |
LG CHEMICAL LTD. |
发明人 |
MOON KWANG YUL;KIM WON SUP;LEE TAE HEE;CHANG JAY HYOK |
分类号 |
A61K31/4375;A61P31/04;C07D;C07D207/22;C07D207/24;C07D207/36;C07D471/04;(IPC1-7):C07D207/24 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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