| 摘要 |
A process is provided for the production of at least one peptide of interest from a biological fluid comprising one or more proteins which contain the amino acid sequence of said peptide, wherein said fluid is contacted with a chromatographic medium to adsorb said protein including the peptide domain, the adsorbed material is hydrolysed to produce said peptide, the medium is washed to remove unbound material, the peptide is desorbed from the chromatographic medium and, optionally, further purified. Preferably, a chromatographic membrane is used and the hydrolysis is preferably carried out enzymatically. Also claimed are peptides, preferably with a biological activity, which are obtainable by the present process. |
