发明名称 |
Method for preventing or controlling cataract |
摘要 |
A method for preventing or treating pathological changes which occur in association with cataract formation in the mammalian eye by protecting lens cells against the cataractogenic effects of transforming growth factor-beta (TGFbeta). Estrogen or an estrogenic substance can be administered to the mammal or directly to or near the eye of the mammal. The means of administration can be by a pharmaceutical composition comprising estrogen, a membranous ocular patch impregnated with estrogen or a lens or lens implant coated or impregnated with estrogen.
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申请公布号 |
US6258856(B1) |
申请公布日期 |
2001.07.10 |
申请号 |
US19990331510 |
申请日期 |
1999.06.25 |
申请人 |
THE UNIVERSITY OF SYDNEY |
发明人 |
CHAMBERLAIN CORAL GWENDA;MCAVOY JOHNSTON WILLIAM;HALES ANGELA MARIA |
分类号 |
A61K9/70;A61K31/05;A61K31/138;A61K31/352;A61K31/365;A61K31/37;A61K31/40;A61K31/47;A61K31/565;A61L27/00;A61P27/12;(IPC1-7):A61K31/565;A61K31/105 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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