| 发明名称 |
D4 receptor selectivity piperazine derivatives |
| 摘要 |
Piperazine derivatives of the formula Iin which R1 and R2 have the meanings given in claim 1 are dopamine ligands with a selectivity for the D4 receptor and are suitable for the treatment and prophylaxis of states of anxiety, depression, schizophrenia, obsessions, Parkinson's disease, tardive dyskinesia, nausea and disorders of the gastro-intestinal tract.
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| 申请公布号 |
US6258813(B1) |
申请公布日期 |
2001.07.10 |
| 申请号 |
US19990254489 |
申请日期 |
1999.03.09 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT |
发明人 |
ARLT MICHAEL;BOTTCHER HENNING;BARTOSZYK GERD;SEYFRIED CHRISTOPH |
| 分类号 |
C07D295/02;A61K31/444;A61K31/495;A61K31/496;A61K31/505;A61K31/506;A61P25/00;A61P43/00;C07D213/38;C07D213/74;C07D239/42;C07D241/04;C07D295/04;C07D295/06;C07D295/073;C07D295/096;C07D295/155;C07D307/82;C07D401/12;C07D405/12;C07D409/10;C07D409/12;C07D409/14;(IPC1-7):A61K31/496;C07D401/06;C07D401/14 |
主分类号 |
C07D295/02 |
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