| 摘要 |
A device for delivering metered aerosols g an active ingredient in solution in a propellant consisting of a hydrofluoroalkane (HFA), selected from 1,1,1,2-tetrafluoroethane (HFA 134a), 1,1,1,2,3,3,3-heptafluoropropane (HFA 227) or mixtures thereof, a co-solvent such as ethanol and optionally a low-volatility component preferably selected from glycerol, propylene glycol polyethylene glycol, oleic acid and isopropyl myristate, said device comprising a flat body with a seat for housing the can, an inhalation mouthpiece and an expansion chamber shaped to create a vortex flow of the aerosol particles expelled by the actuator, wherein the actuator orifice diameter is in the range between 0.30 and 0.50 mm. |
