发明名称 |
Treatment of ischemic brain injuries with brain targetted antioxidant compounds |
摘要 |
A method of reducing oxidative stress in the brain of an organism having a blood brain barrier and suffering an ischemic brain injury, the method comprising the step of administering a compound to the organism, the compound having (a) a combination of molecular weight and membrane miscibility properties for permitting the compound to cross the blood brain barrier of the organism; (b) a readily oxidizable chemical group for exerting antioxidation properties; and (c) a chemical make-up for permitting the compound or its intracellular derivative to accumulate within the cytoplasm of cells. |
申请公布号 |
AU2022501(A) |
申请公布日期 |
2001.07.09 |
申请号 |
AU20010020225 |
申请日期 |
2000.12.26 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF;MOR RESEARCH APPLICATIONS LTD. |
发明人 |
DAPHNE ATLAS;ELDAD MELAMED;DANIEL OFFEN |
分类号 |
A61K31/00;A61K31/16;A61K31/198;A61K31/216;A61K31/223;A61K38/00;A61K38/05;A61K38/06;C07C323/59;C07K5/02 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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