Process for the preparation of polyamines and polyamine derivatives

摘要

Disclosed are processes for the preparation of compounds of the formula (I): H2N-(CH2)n-A-(CH2)m-NH2, or (II): H2N-(CH2)n-NH-C(=NR1)-NH-(CH2)m-NH2, wherein n and m are each independently an integer from 2 to 8; A is selected from the group consisting of -NR1-, -NR1-(CH2)r-NR1- and -NR1-(CH2)r-NR1-(CH2)z-NR1-, wherein r and z are an integer ranging from 2 to 8; and R1 is hydrogen or a protecting group having a carbonyl group.