| 摘要 |
Suspensions, emulsions or dispersions of therapeutically active agents which are water insoluble or water intolerant such as nutritional supplements, herbal products, drugs, bacteria, yeast, vitamins and minerals are prepared as suspensions in edible vegetable oils such as orange, lemon, soybean, cotton seed, peanut, canola corn oil, sunflower, safflower, palm kernel, palm and coconut. The active therapeutic agent may be in crystalline or amorphous form, it may be a liquid as for example an oil such as vitamin E or beta carotene, or a preparation of a comminuted plant structure such as flower, parts, leaf, stem, root or tree bark, or an extract of a dried plant structure, or a freeze dried preparation of a vital bacteria or yeast. The suspension is formed by active mixing of the active agent and oil. To the suspension of the active agent in vegetable oil is added the silica dioxide while actively mixing at 2000-4000 rpm to provide a stable gel, the active agent being uniformly distributed throughout the gel Two to 60 minutes of stirring is more than adequate for all systems. The compositions can be administered orally, sublingually, buccally and topically. For topical administration the preparation of the invention may be formulated as a cream or ointment.
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