NOVEL GUANOSINE TRIPHOSPHATE-BINDING PROTEIN-COUPLED RECEPTORS, GENES THEREOF AND PRODUCTION AND USE OF THE SAME

摘要

Fifteen novel genes sustaining hydrophobic domains, which are seemingly 7 transmembrane domains characteristic to G protein-coupled receptors, are successfully isolated by human tissue cDNA screening. These genes and proteins which are the expression products thereof are usable in screening ligands, screening agonists or antagonists which are useful as drugs, diagnosing diseases in which these gene participate, etc.