发明名称 |
Treating tumors using implants comprising combinations of allogeneic cells |
摘要 |
This invention provides methods and compositions for treating tumors. The cell population is made up of alloactivated lymphocytes from the patient or from one or more third-party donors that are alloactivated in a mixed lymphocyte culture. It can be placed into the tumor bed, or combined with tumor-associated antigen for administration to a distal site as a vaccine. The compositions recruit activated participation of the host Immune system, which then reacts against the tumor and provides a level of ongoing protection. Employing multiple third party donor cells confers particular advantages in terms of effectiveness, timing, and ease of use.
|
申请公布号 |
US2001006631(A1) |
申请公布日期 |
2001.07.05 |
申请号 |
US20010771263 |
申请日期 |
2001.01.26 |
申请人 |
HISERODT JOHN C.;ARTHUR GALE A. |
发明人 |
HISERODT JOHN C.;ARTHUR GALE A. |
分类号 |
A61K38/00;A61K39/00;A61P35/00;C12N5/0783;(IPC1-7):A01N63/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|