发明名称 |
PRODUCTION OF HETEROLOGOUS PROTEINS |
摘要 |
The invention provides a vector for expressing a heterologous gene encoding a polypeptide of interest in a Gram-negative prokaryote and targeting the expressed polypeptide to the outer membrane and/or periplasmic space thereof , the vector comprising nucleic acid encoding a stromal targeting domain (STD) . Also provided are host cells containing the vectors, compositions containing the host cells, and the uses of the compositions and host cells.
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申请公布号 |
CA2395285(A1) |
申请公布日期 |
2001.07.05 |
申请号 |
CA20002395285 |
申请日期 |
2000.12.22 |
申请人 |
THE UNIVERSITY OF WALES, ABERYSTWYTH |
发明人 |
LAMB, DAVID CHRISTOPHER;KELLY, STEVEN LEWIS;KADERBHAI, MUSTAK ALI |
分类号 |
C12N1/21;C12N15/29;C12N15/53;C12N15/70;(IPC1-7):C12N15/63;A01N63/00;A61K38/00;C07K14/415;C12N9/02;C12P21/00;C12Q1/68;G01N33/53 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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