发明名称 MULTIPARTICULATE FORMULATION
摘要 The present invention is related to non-parenteral multiparticulate formulations capable of transporting therapeutic, prophylactic and diagnostic agents across mucosal membranes such as gastrointestinal, buccal, nasal, rectal and vaginal. Formulations comprise a plurality of carrier particles, an agent to be delivered across a mucosal membrane, and a penetration enhancer. The drug is adhered to the surface of the carrier particle or is impregnated within by electrostatic, covalent or mechanical forces.
申请公布号 WO0050050(A8) 申请公布日期 2001.07.05
申请号 WO2000US04662 申请日期 2000.02.23
申请人 ISIS PHARMACEUTICALS, INC.;HARDEE, GREGORY, E.;TILLMAN, LLOYD, G.;MEHTA, RAHUL, C.;TENG, CHING-LEOU 发明人 HARDEE, GREGORY, E.;TILLMAN, LLOYD, G.;MEHTA, RAHUL, C.;TENG, CHING-LEOU
分类号 A61K9/16;A61K47/48;A61K48/00;(IPC1-7):A61K35/64;C12Q1/68;C07H21/02;C07H21/04 主分类号 A61K9/16
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