发明名称 |
SUBSTANCE LIBRARY |
摘要 |
The invention relates to a substance library which can be obtained by reaction of aromatic aldehyde compounds and/or heteroaromatic aldehyde compounds and/or aliphatic aldehyde compounds without an acid proton in a-position in a solution in the presence of a base with secondary amines to produce aminal compounds; reaction of said aminal compounds without any further purification with acid chlorides in an absolute solvent to produce iminium salts; reaction thereof without any further purification in an organic solvent with unsubstituted or substituted naphthol, pyrrole and/or indole compounds; purification and isolation of the compounds thus obtained according to the usual methods and optionally, reaction of the naphthol and/or indol compounds thus obtained in a solution with organic halogen compounds in the presence of a base and optionally, purification by filtration and isolation of the naphthol and/or indol compounds thus obtained according to the usual methods. The invention also relates to the use of said substance library for the detection of active ingredients.
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申请公布号 |
WO0147882(A2) |
申请公布日期 |
2001.07.05 |
申请号 |
WO2000EP12973 |
申请日期 |
2000.12.20 |
申请人 |
GRUENENTHAL GMBH;GERLACH, MATTHIAS;MAUL, CORINNA |
发明人 |
GERLACH, MATTHIAS;MAUL, CORINNA |
分类号 |
B01J19/00;C07D209/00;(IPC1-7):C07D209/00 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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