发明名称 SUBSTANCE LIBRARY
摘要 The invention relates to a substance library which can be obtained by reaction of aromatic aldehyde compounds and/or heteroaromatic aldehyde compounds and/or aliphatic aldehyde compounds without an acid proton in a-position in a solution in the presence of a base with secondary amines to produce aminal compounds; reaction of said aminal compounds without any further purification with acid chlorides in an absolute solvent to produce iminium salts; reaction thereof without any further purification in an organic solvent with unsubstituted or substituted naphthol, pyrrole and/or indole compounds; purification and isolation of the compounds thus obtained according to the usual methods and optionally, reaction of the naphthol and/or indol compounds thus obtained in a solution with organic halogen compounds in the presence of a base and optionally, purification by filtration and isolation of the naphthol and/or indol compounds thus obtained according to the usual methods. The invention also relates to the use of said substance library for the detection of active ingredients.
申请公布号 WO0147882(A2) 申请公布日期 2001.07.05
申请号 WO2000EP12973 申请日期 2000.12.20
申请人 GRUENENTHAL GMBH;GERLACH, MATTHIAS;MAUL, CORINNA 发明人 GERLACH, MATTHIAS;MAUL, CORINNA
分类号 B01J19/00;C07D209/00;(IPC1-7):C07D209/00 主分类号 B01J19/00
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