SUBSTITUTED PYRROLE MANNICH BASES

摘要

The invention relates to substituted pyrrole Mannich bases of general formul a (I), wherein R1=H, a C 1-10-alkyl-, aryl, a heteroaryl- or an aryl, heteroar yl- , CN, Br-, C1 or OH radical bound by a C 1-6 alkylene group, R2=CH(R4)N(R5)(R6), R3, R3', R3'' identically or individually represent H, F , C1, Br, CF3, CN, NO2, SO2NH2, NHR7,SR8, OR9, CO(OR10), CH2CO(OR11), COR15, a C 1-10-alkyl-, aryl-, heteroaryl- aryl radical or a heteroalkyl radical bound by a C 1-6 alkylene group, R4 = an unsubstituted phenyl radical or a phenyl radical substituted at least with C 1-4 alkyl, C 1-3-alkoxy-, halogen-, a method for the production of the above-mentioned compounds, medicaments containing said compounds, and the use of said compounds in the production o f medicaments. Said active ingredients are particularly suitable for pain therapy, and for treating inflammatory and allergic reactions, drug or alcoh ol abuse, diarrhoea, gastritis, ulcers, cardiovascular diseases, urinary incontinence, depressions, states of shock, migranes, narcolepsy, overweight , asthma, glaucoma, hyperkinetic syndrome, lack of drive, bulimia, anorexia, catalepsia, anxiolysis, increasing vigilance and/or increasing libido.