发明名称 |
REDUCTION OF POSTOPERATIVE COMPLICATIONS OF CARDIOPULMONARY BYPASS (CPB) SURGERY |
摘要 |
Patients undergoing cardiopulmonary bypass surgery are treated perioperative ly with methylol transfer agents, such as Taurolidine. Patients undergoing crystallo id cardioplegia who are treated with Taurolidine show reduced levels of IL-6 and increased level s of IL-10 when compared to crystalloid cardioplegia patients administered a placebo. Crystalloid cardioplegia patients administered Taurolidine also show reduced levels of IL-6 and increased levels of IL-10 when compared to blood cardioplegia patients who were administered Taurolidine.
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申请公布号 |
CA2330359(A1) |
申请公布日期 |
2001.07.05 |
申请号 |
CA20012330359 |
申请日期 |
2001.01.05 |
申请人 |
ED GEISTLICH SOHNE AG FUR CHEMISCHE INDUSTRIE |
发明人 |
PFIRRMANN, ROLF W.;REDMOND, H. PAUL |
分类号 |
C07D285/18;A61K31/00;A61K31/549;A61K45/00;A61K45/06;A61M1/36;A61P7/00;A61P9/00;A61P9/06;A61P31/00;A61P31/04;A61P41/00;A61P43/00;(IPC1-7):A61K31/549 |
主分类号 |
C07D285/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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