| 发明名称 |
Inactivated dengue virus vaccine |
| 摘要 |
An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models.
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| 申请公布号 |
US6254873(B1) |
申请公布日期 |
2001.07.03 |
| 申请号 |
US19950423338 |
申请日期 |
1995.04.17 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY |
发明人 |
PUTNAK J. ROBERT;ECKELS KENNETH;DUBOIS DORIS R. |
| 分类号 |
A61K39/12;C12N7/04;(IPC1-7):C07K14/18 |
主分类号 |
A61K39/12 |
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