Use of substituted azaspirane in the treatment of asthma

摘要

A substituted azaspirane of formula (I) or a pharmaceutically acceptable salt, solvate or hydrate thereof is used in the manufacture of a medicament for use in treating asthma. In formula (I): n is 3 to 7; m is 1 or 2; R1 and R2 are independently H or alkyl provided that the total number of carbon atoms contained by R1 and R2 when taken together is 5 to 10 or R1 and R2 form a cyclic alkyl group of 3 to 7 carbon atoms; R3 and R4 are independently H or alkyl or R3 and R4 are joined together with the nitrogen atom to which they are attached to form a heterocyclic of 5 to 8 atoms.