use of lipoprotein and a type 2T independent antigen to induce an immune response to the antigen

摘要

A method of inducing or enhancing an immune response to polysaccharides or other T cell-independent antigen by the co-administration of the antigen with bacterial lipoproteins (including covalent attachment of the antigen and lipoproteins). In a preferred embodiment, the lipoprotein is lipoprotein D.