发明名称 An anti-viral/anti-cancer pharmaceutical composition comprising either an N-chlorophenylcarbamate or an N-chlorophenylthiocarbamate and N-phosphonoglycines
摘要 Provided is a pharmaceutical composition for treating viral infections or inhibiting the growth of tumors or cancers comprising a mixture of: 1 An N-chlorophenylcarbamate or an N-chlorophenylthiocarbamate of the formula depicted wherein n is from 1 to 3; X is either O or S; and R is hydrogen, alkyl, alkenyl, cyclohexyl or phenalkyl; or a salt thereof; and 2 An N-phosphonoglycine of the formula depicted wherein X is hydroxy, alkoxy or chloroalkoxy, alkenoxy, cyclohexyloxy, morpholino, pyrrolidinyl, piperidino and NHR', where R' is hydrogen, alkyl alkenyl, cyclohexyl, phenalkyl, phenyl, chlorophenyl and anisyl; Y and Z are each hydrogen or alkyl; and R is hydrogen, formyl, acetyl, benzoyl, nitrobenzoyl and chlorobenzoyl; or a salt thereof; and wherein the ratio of (1) to (2) is from 10:1 to 1:10 on a mole weight basis.
申请公布号 NZ306270(A) 申请公布日期 2001.06.29
申请号 NZ19960306270 申请日期 1996.04.11
申请人 THE PROCTER & GAMBLE COMPANY 发明人 CAMDEN, JAMES BERGER
分类号 A61K31/66;A61K31/27;A61P31/12;A61P35/00;(IPC1-7):A61K31/662 主分类号 A61K31/66
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