FLOW-THRU CHIP CARTRIDGE, CHIP HOLDER, SYSTEM AND METHOD THEREOF

摘要

A system for performing hybridization assays comprises a cartridge for housi ng a flow through device, where the cartridge includes a test fluid chamber for facilitating a substantially uniform floe of a test fluid mixture through th e flow through device, and a fluidics station to deliver the test fluid mixtur e to the cartridge. The cartridge has a chip holder that holds the flows-throu gh device, which has an array of microchannel passages. The chip holder has a support for placement of the flow though device, the test fluid chamber for directing a substantially uniform flow through device, and a first port that receives the test fluid mixture. The cartridge has a sealing system for preventing the leakage of the test fluid around the flow through device. The test fluid chamber is defined in part by a spade-like surface having an inle t for the test fluid mixture.