| 发明名称 |
HERPES SIMPLEX VIRUS-1 GLYCOPROTEIN C MUTANTS FOR TREATING UNWANTED HYPERPROLIFERATIVE CELL GROWTH |
| 摘要 |
The present invention relates to pharmaceutical compositions, kits, and methods of use thereof, comprising, a mutant human herpes simplex virus, which is cytopathic to susceptible target cells, such as neoplastic cells. Preferably, the virus does not produce a functionally active wild-type gC polypeptide coded for the UL44 gene.
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| 申请公布号 |
WO0145737(A2) |
申请公布日期 |
2001.06.28 |
| 申请号 |
WO2000US34621 |
申请日期 |
2000.12.18 |
| 申请人 |
ONYX PHARMACEUTICALS, INC. |
发明人 |
LAQUERRE, SYLVIE;HERMISTON, TERRY |
| 分类号 |
A61K35/76;A61P35/00;C07K14/035;C12N7/00;C12N7/01;C12N7/04;(IPC1-7):A61K39/12 |
主分类号 |
A61K35/76 |
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