发明名称 A PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 2,2-DIALKYL-4-SUBSTITUTED PIPERIDINES
摘要 <p>The present invention provides a process for preparing a compound of formula (I): wherein R?1 and R2¿ each independently represent C¿1?-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R?-M+¿ wherein M+ is a suitable cation.</p>
申请公布号 WO2001046142(A1) 申请公布日期 2001.06.28
申请号 US2000032424 申请日期 2000.12.06
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