摘要 |
The preparation of mono-cationic salt of N,N'-bis(2-hydroxybenzyl)- ethylenediamine-N,N'-diacetic acid (HBED) and HBED itself is disclosed. In particular, the invention relates to the hydrolysis of the t-butyl ester of HBED with a weak acid, such as formic acid, to form HBED, and the subsequent reaction with an equimolar amount of a base to form the mono-cationic salt.
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