发明名称 |
USE OF BIOACTIVE METABOLITES OF GEPIRONE FOR THE TREATMENT OF PSYCHOLOGICAL DISORDERS |
摘要 |
Bioactive gepirone metabolites, such as 3-OH gepirone (4,4,-dimethyl-3-hydro xy- 1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione), and their pharmaceutically acceptable salts and hydrates, can be used to alleviate psychological disorders or the symptoms thereof. The use of these compounds provides advantages over other therapeutic azapirones as they possess superi or bioavailability, faster onset of action, and more stable plasma levels when administered to a mammal.
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申请公布号 |
CA2395458(A1) |
申请公布日期 |
2001.06.28 |
申请号 |
CA20002395458 |
申请日期 |
2000.12.18 |
申请人 |
FABRE-KRAMER PHARMACEUTICALS, INC.;YEVICH, JOSEPH P.;RUEDIGER, EDWARD H. |
发明人 |
FABRE, LOUIS F.;KRAMER, STEPHEN J.;YEVICH, JOSEPH P.;RUEDIGER, EDWARD H. |
分类号 |
C07D401/12;A61K31/506;A61P25/22;A61P25/24;A61P25/28;A61P25/32;(IPC1-7):A61K31/506 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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