发明名称 |
COMPOUNDS AND USE THEREOF TO MODIFY TRANSPORT ACROSS CELL MEMBRANES |
摘要 |
The invention provides the use of a compound capable of preferential interaction with plasma membrane lipid microdomains (PMLMs) as enhancers of transport processes across endothelial, epithelial and mesothelial membranes (ie including blood-brain-blood barrier and gastrointestinal mucosal membranes). When associated with therapeutic agents, the compounds act as transport vehicles. When the compounds interact with PMLMs in such a way as to inhibit transport across the membrane, the compounds function as anti- infective agents.
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申请公布号 |
CA2394877(A1) |
申请公布日期 |
2001.06.28 |
申请号 |
CA20002394877 |
申请日期 |
2000.12.21 |
申请人 |
BIOVECTOR SOLUTIONS LIMITED |
发明人 |
O'SHEA, PAUL;HARRIS, ROY |
分类号 |
A61K47/42;A61K38/00;A61K38/08;A61K38/10;A61K45/00;A61K45/06;A61K47/48;A61P31/00;A61P43/00;C07K7/06;C07K7/08;C07K14/00;(IPC1-7):C07K7/08 |
主分类号 |
A61K47/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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