| 发明名称 |
A PROCESS FOR PREPARING TRANS-2,4-DISUBSTITUTED PIPERIDINES |
| 摘要 |
<p>The present invention provides a process for preparing a compound of formula (I), wherein R represents C1-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II), with a suitable crown ether and a suitable base followed by addition of a compound of formula R<->M<+> wherein M<+> is a suitable cation.</p> |
| 申请公布号 |
WO0146143(A1) |
申请公布日期 |
2001.06.28 |
| 申请号 |
WO2000US32428 |
申请日期 |
2000.12.06 |
| 申请人 |
ELI LILLY AND COMPANY;GODFREY, ALEXANDER, GLENN;PEDERSEN, STEVEN, WAYNE |
发明人 |
GODFREY, ALEXANDER, GLENN;PEDERSEN, STEVEN, WAYNE |
| 分类号 |
C07D211/12;C07D211/22;C07D409/04;(IPC1-7):C07D211/12 |
主分类号 |
C07D211/12 |
| 代理机构 |
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