发明名称 Solutions of human procalcitonin
摘要 Isolated, preferably recombinant, polypeptides (I) containing the amino acid sequence for human procalcitonin (hpCT), are new. Isolated, preferably recombinant, polypeptides (I) containing the amino acid sequence for human procalcitonin (hpCT), are new, where hpCT has the sequence: APFRSALESSPADPATLSEDEARL(L/R)LAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTC MLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN Independent claims are also included for the following: (1) recombinant production of hpCT; (2) a plasmid containing at least one nucleic acid (II) encoding (I); (3) an animal, plant, isolated human or prokaryotic cell that expresses (I); (4) a sterile injectable solution containing (I); (5) preparation of antibodies (Ab) by immunization with (I); (6) a test kit containing at least one (I); (7) a control and/or standard solution containing at least one (I); and (8) a solution containing at least one (I) and at least one sterol ester of formula (II). R1OCO-R2-COO(CH2CH2)n-CH2CH2-OH R1 = sterol; n = 1-200; and R2 = 4-8C aliphatic or aromatic ring, optionally with at least one atom replaced by nitrogen, sulfur or oxygen, or a 0-12C linear or branched chain.
申请公布号 EP1111050(A2) 申请公布日期 2001.06.27
申请号 EP20000125719 申请日期 2000.11.24
申请人 DADE BEHRING MARBURG GMBH 发明人 ALTHAUS, HARALD;HAUSER, HANS PETER, DR.
分类号 C12N15/09;A61K9/08;A61K38/00;A61K38/23;A61K39/395;A61K47/28;A61K47/42;A61P3/14;A61P5/22;A61P35/04;C07J9/00;C07K14/585;C07K16/26;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/16;C12P21/02;C12P21/08;(IPC1-7):C12N15/16;G01N33/74 主分类号 C12N15/09
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