发明名称 |
Camp-responsive transcriptional enhancer binding protein |
摘要 |
This invention is directed toward the characterization and cloning of a cAMP-responsive transcription enhancer binding protein (CREB). This protein, CREB, is a transcriptional activator which activates transcription in eukaryotic cells. This CREB protein can be used to increase or decrease production of proteins by stimulating expression of a recombinant gene that is operably-linked to the CRE enhancer element and responsive to cAMP.
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申请公布号 |
US6251667(B1) |
申请公布日期 |
2001.06.26 |
申请号 |
US19990252658 |
申请日期 |
1999.02.19 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
HABENER JOEL F.;HOEFFLER JAMES P. |
分类号 |
C07K14/47;C12N15/12;C12N15/67;C12N15/85;(IPC1-7):C12N5/10;C07K14/435 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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