发明名称 |
Compositions and methods for alleviating impaired mental function, memory loss and reducing recovery time in anaesthetized mammals |
摘要 |
Composition and methods of alleviating impaired mental function and memory loss in mammals and reducing the recovery time from anaesthesia in age mammals, comprising treating the mammal with a non-toxic, enhancing effective amount of a cell membrane permeant calcium buffer. The buffer is preferably a calcium ion chelating agent having a KD selected from the range 1x10-4 to 1x10-8 Molar and being essentially calcium ion-selective over other metal ions. A most preferred buffer is BAPTA-AM.
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申请公布号 |
US6251942(B1) |
申请公布日期 |
2001.06.26 |
申请号 |
US19990316203 |
申请日期 |
1999.05.21 |
申请人 |
CARLEN PETER LOUIS |
发明人 |
CARLEN PETER LOUIS;JANUS CHRISTOPHER GEORGE;EL-BEHEIRY HOSSAM |
分类号 |
A61K45/00;A61K31/00;A61K31/195;A61K31/198;A61K31/215;A61K31/225;A61P25/28;A61P43/00;(IPC1-7):A61K31/195 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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